Dosage: Initial dose: The recommended starting dose is often 150mg per day, divided into two or three doses.
Mechanism of action: Pregabalin acts by binding to the α2-δ subunits of voltage-gated calcium channels in the central nervous system, thereby reducing the release of excitatory neurotransmitters such as glutamate. This mechanism decreases neuronal excitability, contributing to its anticonvulsant, analgesic, and anxiolytic effects.




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