INDICATIONS:
- Jaundice
- Cholestasis
- Cirrhosis
- Chronic hepatitis
- Steatosis
- Alcohol-induced liver damage
- Dissolution of cholesterol gallstones
- Primary biliary cholangitis (PBC)
- Cholestatic liver disease
- Drug-induced liver toxicity
- Hepatic canalicular disease
- Chronic inflammatory liver disease
DOSAGE:
The usual dosage is 8 to 10 mg/kg/day.
Do not exceed 900 mg/day.
ADDITIONAL INFORMATION:
- Stimulation of hepatobiliary secretion (choleretic effects); increases bile acid biosynthesis.
- Cholesterol regulation – decreases cholesterol absorption and biliary secretion. Solubilization of cholesterol gallstones (oral litholysis) and prevention of gallstone formation.
- Cytoprotection of hepatocytes and cholangiocytes against cytotoxic bile acids.
- Regulation of glucose metabolism.
- Immunomodulatory effects
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